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Type 2 Diabetes Management Guidelines

Sulfonylureas

  • Titration of sulfonylureas
  • Can double dose of sulfonylureas every 1 -2 weeks until maximum of glipizide 10 mg bd or gliclazide160 mg bd
  • Titration is more safely done with monitoring of blood glucose levels before and 2 hours after meals to ensure no postprandial hypoglycaemia
  • Previous episodes of severe hypoglycaemia
  • Significant hypoglycaemic unawareness
  • Elderly and/or with cognitive impairment
  • Chronic renal and/or liver impairment
  • Malnutrition including reduced oral intake and significant alcohol use